Tissue Protective Cytokines (TPCs)

General Features of
Tissue Protective Cytokines
Restore vascular autoregulation
Inhibit excitatory transmitter release
Maintain synaptic transmission
Inhibit apoptosis
Reduce inflammatory response
Enhance tissue repair
Recruit stem cells
Increase resistance to
oxidative injury (preconditioning)
Warren Pharmaceuticals' tissue protection technology centers on tissue protective cytokines (TPCs), novel and proprietary protein molecules with the ability to rescue cells otherwise destined for removal through the mechanisms described above, and promoting the normalization of damaged tissues surrounding the primary site of injury or disease, leading to a faster and more complete recovery.

TPCs have been shown, in animal models, to prevent cell-death (anti-apoptotic), reduce inflammation (anti-inflammatory), and improve autoregulation of blood vessels in a number of tissues, in particular the retina, kidney, heart, brain and the spinal cord.

In addition, TPCs have been shown to have potent stem cell recruitment activity which has been highly correlated with enhanced tissue repair.



The extent and severity of tissue damage and scar formation secondary to a site of disease or injury are markedly reduced in the presence of TPCs.

Return